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SCIENCE AND RESEARCH

About Insulin Resistance

Insulite Research
Insulin Resistance - Risk of Early Heart Disease Insulin Resistance - Risk of Early Heart Disease
- Reuters Aug 9, 2001
  Physicians and nurses use and recommend dietary supplements: report of a survey.
- Annette Dickinson, Nicolas Boyon, Andrew Shao. Nutrition Journal 2009, 8:29, doi:10.1186/1475-2891-8-29
Alternative Therapies for Type 2 Diabetes Alternative Therapies for Type 2 Diabetes
- Lucy Dey MD, Chun-Su Yuan MD PHD
  The role of insulin, insulin growth factor, and insulin-degrading enzyme in brain aging and Alzheimer's disease.
-Messier C, Teutenberg K.School of Psychology, University of Ottawa, Neural Plast. 2005;12(4):311-28
  Risk Factors and Life Expectancy Project, University of Buffalo, results presented at the annual meeting of the Society for Epidemiological Research.
-Paolo Muti MD, Jain Liu, Maurizio Trevisan MD, Alessandro Menotti, University of Buffalo
  Relationship between Insulin Resistance, weight loss and coronary heart disease risk in healthy, obese women
-McLaughlin T, Abbasi F, Kim HS, Lamendola C, Schaaf P, Reaven G. Department of Medicine, Stanford University School of Medicine Stanford, CA, USA
Alternative Therapies for Type 2 Diabetes F as in Fat: How Obesity Policies are Failing in America
- Trust for America's Health, 2005.
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Insulite Pre-SensitX :

Gymnema Sylvestre:

Blood Sugar Control:

Hypoglycemic Actions:

Insulite Research Science
  • Hypoglycaemic activity of an indigenous drug (Gymnema sylvestre, 'Gurmar') in normal and diabetic persons.
  • Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.
  • Antihyperglycemic effects of gymnemic acid IV, a compound derived from Gymnema sylvestre leaves in streptozotocin-diabetic mice.

Enhances Insulin Action:

  • Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.
  • Antihyperglycemic effects of gymnemic acid IV, a compound derived from Gymnema sylvestre leaves in streptozotocin-diabetic mice.

Anti-Diabetic Action:

  • Enzyme changes and glucose utilization in diabetic rabbits: the effect of Gymnema sylvestre, R.Br.
  • Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.

Decreases HbA1c:

Pre-diabetes research
  • Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.

Beta-Cell regeneration/repair:

  • Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.

Bitter Melon (Momardica Charantia):

Blood sugar lowering:

Anti-Diabetic:

PRED Insulite Laboratories Researc

Improved Glucose Tolerance:

Lipid Lowering Actions:

  • Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook. fruit powder in alloxan-diabetic rats.
  • Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats.
  • Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats.
  • Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats.
  • Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats.

Decreased Post Prandial Glucose:

Decreased Fat Tissue Accumulation:

  • Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines.

Berberis Aquifolium (Oregon Grape Root):

Blood Glucose Lowering:

Insulite Science and Research

Raises Insulin Sensitivity:

Stimulates Insulin Secretion:

Compared with Metformin in glucose lowering capability:

General Information about herbs for controlling pre-diabetes:

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Science and Research Insulite Laboratories

About Alpha Lipoic Acid

  • Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
  • Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by alpha-lipoic acid in 3T3-L1 adipocytes.
  • Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: current evidence from clinical trials.
  • Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy.
  • Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes.

Omega-3 and Lipid Profiles

  • Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses.
  • Docosahexaenoic and eicosapentaenoic acids in plasma phospholipids are divergently associated with high density lipoprotein in humans.
  • Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids.
  • Eicosapentaenoic acid is primarily responsible for hypotriglyceridemic effect of fish oil in humans.
  • Long-term effects of fish oil on insulin resistance and plasma lipoproteins in NIDDM patients with hypertriglyceridemia.
  • Increased n-6 polyunsaturated fatty acids do not attenuate the effects of long-chain n-3 polyunsaturated fatty acids on insulin sensitivity or triacylglycerol reduction in Indian Asians.

Omega-3 and Cardiovascular Disease (CVD)

Science and Research Insulite Laboratories

Omega-3 and Hypertension

Omega-3 and Insulin Resistance

Omega-3 and the Reduction in Inflammatory Markers
Associated with CVD

Science and Research Insulite Laboratories
  • C-reactive protein is independently associated with fasting insulin in nondiabetic women.
  • Insulin resistance, inflammation, and serum fatty acid composition.
  • Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women.
  • Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction.
  • Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women.
  • Background diet influences the anti-inflammatory effect of alpha-linolenic acid in dyslipidaemic subjects.
  • Diet composition and insulin action in animal models.
  • Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women.
  • Dietary fatty acids affect plasma markers of inflammation in healthy men fed controlled diets: a randomized crossover study.

Neurological Impact of Omega-3's

Science and Research Insulite Laboratories

Banaba Leaf

 

Food Addiction



Diabetes



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Diabetes and Its Awful Toll Quietly Emerge as a Crisis"
New York Times
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Diabetes or Pre-Diabetes Now Strikes One in Four Americans:
The number of Americans with diabetes has grown to about 24 million people, or roughly 8 percent of the U.S. population. Read more...
7/25/2008, Mercola.com
"I have been on the Insulite Pre-Diabetes System for 6 months now. I have lost 52.5 lbs and am walking 5 miles a day, 6 days a week. I feel great! I still have a hard time believing that this has worked so well and so easily. I have tried to lose weight for years and had even come to the point of gaining weight while fasting.

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"Simply losing 5-7% of your body fat (typically 10-15 pounds) and increasing your physical activity by taking a brisk walk 4-5 times a week can reduce your risk of developing Type II Diabetes by almost 60%."
Diabetes Prevention Program study 2001, study funded by the National Institute of Child Health and Human Development, et al.
Pre-diabetes Newsletter Archive
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I am so excited about the positive changes in my health and I can't wait to see where I am six months from now, yet alone the year. Thank you again!"
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  Stuarts Draft, VA
"...approximately 90% of overweight Hispanic children with a family history for type 2 diabetes have at least one feature of the metabolic syndrome and 30% possess the metabolic syndrome.

Our results support the view that improving insulin resistance may be crucial in the prevention of both type 2 diabetes and premature cardiovascular disease in this at-risk subpopulation of Hispanic youth."
Cruz ML, Weigensberg MJ, Huang TT, Ball G, Shaibi GQ, Goran MI.,J Clin Endocrinol Metab. 2004 Jan;89(1):108-13.
Article by Dr. Sheri Colberg, Phd, FACSM
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You are all very supportive, even though I am on the other side of the world (Australia). I am very glad that I am on your product, your weekly messages are also very encouraging, when I am finding things a bit harder. Thank you for everything."
Anna
  Perth, Australia

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