PRE-DIABETES AND HEART DISEASE
Insulin Resistance-linked obesity can
be a root cause of Pre-Diabetes, which,
if neglected, may lead to Type 2 Diabetes,
a severely increased risk factor for heart disease.
When the body becomes Insulin Resistant, it begins a cycle
which leads to the release of more and more insulin to compensate
for an increase in blood sugar levels. This elevation in
insulin is called hyperinsulinemia, as pancreatic insulin
secretion rises to maintain normal levels of glucose in the
blood. An excess of insulin in the blood stream and an increased
risk of high cholesterol levels are major risk factors for
the onset of Pre-Diabetes and damage to the cardiovascular
Hyperinsulinemia can stimulate lipid storage (fat storage
throughout the body) and alter lipoprotein levels thereby
increasing cholesterol. The resulting excess of insulin also
encourages the liver to produce more of the blood lipids
called triglycerides, which store fat for energy and pass
through the blood stream to the tissues.
This blood fat disorder is called Dyslipidemia, which fosters
plaque build-up in artery walls. Dyslipidemia is diagnosed
when LDL (low-density lipoprotein or "bad" cholesterol) is
high, HDL (high density lipoprotein or "good" cholesterol) is
low, triglycerides levels are high or there a combination
of all these factors, which are associated with an increased
risk for heart disease.
Additionally, LDL cholesterol particles seen in people who
suffer from Insulin Resistance and Pre-Diabetes are
smaller and more dense than those of people without this
condition. This factor has been directly linked to an increased
risk of Cardiovascular Disease, heart attacks and stroke,
although the exact cause of the relationship is unclear.
Increased LDL cholesterol is one of the underlying symptoms
that can trigger a blood test diagnosis of reversible Pre-Diabetes,
which, if neglected, can lead Type 2 Diabetes. This latter
condition can only be managed – not reversed – and
may require daily insulin. Obesity, elevated insulin, high
blood lipids, poor diet and physical inactivity are known
to have an effect on the development of high levels of cholesterol.
Another factor in Pre-Diabetes and heart disease is the
role of inflammation, which is part of the body's immune
system. Inflammation triggers a defense response to harmful
stimuli or injury by sending specialized blood cells to damaged
areas where they attack "invaders" like the renegade
molecules called "free radicals" and clean up dead
and dying cells.
In the case of inflammation and Pre-Diabetes, the "invader" is
thought to be excess levels of insulin, which can be caused
by the imbalance of blood glucose and insulin called Insulin
Inflammation can take an external form like the reddened,
tender skin which draws attention to a splinter in your finger.
Or it can be an unseen, internal process in response to something
harmful like high blood pressure.
To combat internal harm, inflammation produces C-reactive
protein (CRP), which, unfortunately, can damage the arteries
by helping to form plaque while attempting to tackle a long-term
condition like high blood pressure or high LDL cholesterol
levels - often accompanying symptoms of Pre-Diabetes.
Plaque is a substance that attaches itself to artery walls,
damaging those walls and seriously impairing blood flow,
which can lead to a heart attack or stroke. A blood test
measures CRP levels and the higher that level is, the more
at risk you are from cardiovascular disease. There's contradictory
evidence about whether CRP levels and Insulin Resistance
are closely linked.
Research about inflammation is often cutting edge material
that still needs ample verification. But scientists are gathering
data that inflammation precedes and may predict reversible
Pre-Diabetes, which, if left unchecked, can lead to the onset
of Type 2 Diabetes.
Previous research had already linked inflammation to heart
disease and obesity, which are both common in people with
Pre-Diabetes. To learn more, click
on Inflammation, Insulin Resistance and Pre-Diabetes.
Although there are approved drugs that can help lower cholesterol
levels, there are currently no drugs that will completely
reverse the symptoms of Insulin Resistance and Pre-Diabetes.
The same is true of related conditions like Metabolic Syndrome (Syndrome
X) and the hormonal disorder called Polycystic Ovarian
Syndrome (PCOS), a leading cause of female infertility
as well as menstrual irregularity, skin conditions and excess
body and facial hair. All Insulin Resistance-linked
disorders are increased risk factors for Cardiovascular Disease
leading to a heart attack or stroke.
You must rely on a multi-faceted approach to improving
these conditions. A complete system is recommended, including
nutraceuticals (vitamins, herbs and minerals that are
disease-specific), a realistic exercise program combined
with nutritional guidance and a support system that will
help you adopt a healthier lifestyle choices.
Click here to
read about the new scientific breakthrough called the Insulite Pre-Diabetes System,
which can help reverse Pre-Diabetes, and
prevent the onset of Type 2 Diabetes and its attendant risk
of heart disease.
The system features a series of scientifically-designed
formulations like RejuvenX, which includes CoQ10, a powerful
anti-oxidant that lowers glucose and insulin levels, and
Vitamin C to reduce damage to arteries.
You may be interested in some related information
on Pre-Diabetes and the Insulite Pre-Diabetes System:
to read about Pre-Diabetes and Hypertension (High Blood